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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Tomás Esparza | 182 | 2012-2039 | |
| 2 | Jerry Collins | 141 | 2007-2024 | |
| 3 | Arturo Ramírez | 111 | 2013-2029 | |
| 4 | José Santos | 109 | 2012-2026 | |
| 5 | Ron Gómez# | 96 | 2024-2039 | |
| 6 | Juan Martínez | 95 | 2012-2025 | |
| 7 | Javier Gómez | 92 | 2014-2025 | |
| 8 | Gary Edwards | 84 | 2009-2018 | |
| 9 | Jorge Alou | 83 | 2021-2039 | |
| 9 | Alfredo García | 83 | 2015-2028 | |
| 11 | Jorge Valentín# | 82 | 2030-2039 | |
| 12 | Jesús Cantú# | 81 | 2019-2039 | |
| 13 | Jorge Escamilla# | 80 | 2025-2039 | |
| 14 | Alonso Flores# | 77 | 2030-2039 | |
| 15 | Luis Cantú | 75 | 2022-2027 | |
| 16 | Miguel Cordero# | 74 | 2027-2039 | |
| 17 | Gustavo Luján# | 73 | 2029-2039 | |
| 18 | Eiichi Nakao | 72 | 2010-2020 | |
| 19 | Tony Salazar# | 70 | 2029-2039 | |
| 19 | Clark Vallés# | 70 | 2029-2039 | |
| 21 | Joe Rivera | 65 | 2029-2038 | |
| 22 | Manuel Ávila# | 60 | 2021-2028 | |
| 23 | Gabriel Gutiérrez | 58 | 2011-2020 | |
| 23 | Rafael Quintero | 58 | 2027-2035 | |
| 25 | Ángel Valdéz | 57 | 2017-2026 | |
| 26 | Mal Benton | 54 | 2017-2029 | |
| 26 | José Méndez | 54 | 2012-2025 | |
| 28 | Juan Gonzáles# | 52 | 2023-2032 | |
| 29 | José Gonzáles# | 51 | 2027-2039 | |
| 30 | Ken Martínez# | 49 | 2031-2039 | |
| 30 | Carlton Minor# | 49 | 2027-2039 | |
| 32 | Pedro Ramírez | 47 | 2007-2016 | |
| 33 | José Morín | 46 | 2016-2020 | |
| 34 | Alonso González | 44 | 2019-2031 | |
| 35 | Emílio Alvarado | 42 | 2007-2012 | |
| 35 | Ted Larson# | 42 | 2034-2039 | |
| 37 | Ángel López# | 41 | 2031-2039 | |
| 37 | Manuel Piñal# | 41 | 2032-2039 | |
| 39 | León Alonzo# | 40 | 2025-2039 | |
| 39 | Enrique Cruz | 40 | 2020-2034 | |
| 39 | Iván Rosa# | 40 | 2028-2039 | |
| 42 | Walt Porter# | 38 | 2027-2032 | |
| 43 | Jay Black# | 37 | 2021-2039 | |
| 43 | Bennett Dean | 37 | 2007-2022 | |
| 43 | Xavier González | 37 | 2014-2036 | |
| 43 | Manuel Macías# | 37 | 2032-2039 | |
| 47 | Jesús Lorenzo# | 36 | 2031-2039 | |
| 48 | Juan Olivares | 35 | 2007-2010 | |
| 48 | Fernando Vásquez# | 35 | 2030-2039 | |
| 50 | José López | 34 | 2009-2018 | |
| 50 | Johnny MacKinney | 34 | 2017-2020 | |
| 52 | Jerome Beaton | 33 | 2007-2013 | |
| 52 | Alberto Caballero# | 33 | 2036-2039 | |
| 52 | Junior Castillo | 33 | 2014-2032 | |
| 52 | António López | 33 | 2020-2030 | |
| 52 | António Rodríguez# | 33 | 2028-2039 | |
| 57 | Errol Marque# | 32 | 2026-2039 | |
| 57 | Ricardo Peña | 32 | 2021-2029 | |
| 57 | Dave Smith | 32 | 2009-2012 | |
| 60 | Juan Alvarado | 31 | 2019-2038 | |
| 60 | Rafael Delgado# | 31 | 2032-2039 | |
| 60 | David López | 31 | 2014-2037 | |
| 60 | Fred Negrón | 31 | 2013-2015 | |
| 60 | Domingo Pérez# | 31 | 2036-2039 | |
| 60 | Ricardo Tovar | 31 | 2007-2017 | |
| 66 | Santiago Carmona | 30 | 2009-2014 | |
| 66 | Orlando Ruíz# | 30 | 2032-2039 | |
| 66 | Arturo Sánchez | 30 | 2008-2010 | |
| 69 | Aurelio Baca# | 29 | 2036-2039 | |
| 69 | Manuel Espinoza | 29 | 2008-2011 | |
| 69 | Francisco González | 29 | 2028-2031 | |
| 72 | Mario García# | 28 | 2025-2039 | |
| 72 | Armando López# | 28 | 2029-2035 | |
| 72 | Cristián Rosado | 28 | 2017-2028 | |
| 75 | Mike Anderson# | 26 | 2029-2039 | |
| 75 | Kevin Orozco# | 26 | 2028-2039 | |
| 77 | Martín Martínez# | 25 | 2028-2039 | |
| 77 | José Rodríguez | 25 | 2028-2037 | |
| 77 | Juan Román | 25 | 2014-2024 | |
| 80 | José Arroyo | 24 | 2007-2008 | |
| 80 | Cristián Básquez | 24 | 2007-2009 | |
| 80 | José De La Cruz# | 24 | 2032-2039 | |
| 83 | Javier Chavez | 23 | 2009-2011 | |
| 83 | Lúcio Medina | 23 | 2018-2019 | |
| 83 | Rafael Salas# | 23 | 2023-2039 | |
| 86 | Juan Flores | 22 | 2012-2021 | |
| 86 | Guillermo Mejía | 22 | 2028-2030 | |
| 88 | Pedro Concepción | 21 | 2018-2020 | |
| 88 | Luis Díaz | 21 | 2007-2019 | |
| 88 | Greg Manuel# | 21 | 2037-2039 | |
| 88 | Manolo Morán# | 21 | 2034-2036 | |
| 88 | César Rodríguez | 21 | 2007-2011 | |
| 88 | Edgardo Rojas | 21 | 2024-2028 | |
| 94 | Eduardo Camacho# | 20 | 2027-2039 | |
| 94 | Armando Rodríguez# | 20 | 2030-2039 | |
| 94 | Jaime Sáenz | 20 | 2007-2009 | |
| 97 | Nathan Barton | 19 | 2015-2020 | |
| 97 | Edward Cooley | 19 | 2015-2016 | |
| 97 | Pedro Donjuan# | 19 | 2029-2033 | |
| 97 | Norm Hawk | 19 | 2014-2021 |
